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Could MS Have Links to the Herpes Virus?

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By Robert Preidt
HealthDay Reporter


MONDAY, Dec. 2, 2019 (HealthDay News) — A variant of a standard herpes virus could play a task within the growth of multiple sclerosis (MS), Swedish researchers say.

They analyzed the blood of about 8,700 MS sufferers and a management group of more than 7,200 individuals with out MS. They had been on the lookout for antibodies towards proteins of two variants (A and B) of human herpesvirus 6 (HHV-6), which has been linked with MS.

MS sufferers had been 55% more prone to have antibodies towards the HHV-6A protein than the management group.

The researchers additionally regarded a sub-group of virtually 500 individuals who didn’t have MS. The danger of creating MS more than doubled for many who’d had a HHV-6A an infection. The youthful they had been when the virus was discovered of their blood, the higher their future MS danger.

The findings recommend that HHV-6A could play a task within the growth of MS, in line with the authors of the research revealed Nov. 26 within the journal Frontiers in Immunology.

MS is an autoimmune disease that impacts the central nervous system, inflicting weak point, motion issues and tremors. Its trigger is unclear, however one concept is {that a} virus methods the immune system to assault the physique’s personal tissue.

Though earlier analysis linked HHV-6 with MS, it could not distinguish between the 6A and 6B variants. Researchers on this new research had been ready to do this.

“This is a big breakthrough for both the MS and herpes virus research,” stated research co-senior writer Anna Fogdell-Hahn, an affiliate professor of medical neuroscience at Karolinska Institute in Stockholm.

“For one, it supports the theory that HHV-6A could be a contributing factor to the development of MS,” Fogdell-Hahn stated in an institute information launch. “On top of that, we are now able, with this new method, to find out how common these two different types of HHV-6 are, something we haven’t been able to do previously.”

It’s believed that as many as 80% of youngsters are contaminated with the HHV-6 virus earlier than they’re 2 years outdated, and plenty of have antibodies towards it for the remainder of their lives.

“Both HHV-6A and 6B can infect our brain cells, but they do it in slightly different ways. Therefore, it is now interesting to go forward and attempt to map out exactly how the viruses could affect the onset of MS,” Fogdell-Hahn stated.



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Sources

SOURCE: Karolinska Institute, information launch, Nov. 26, 2019




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